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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of MALAT1
ncRNA name MALAT1
ncRNA Category lncRNA
ID 378938
Ensembl ENSG00000251562
Synonyms HCN, LINC00047, MALAT-1, NCRNA00047, NEAT2, PRO1073, mascRNA
Disease name retinoblastoma (RB)
Species Homo sapiens
Tissues/Cell_line human RPE cells and human RB cell lines Y79 (HTB-18), WERI-RB1 (HTB-169), SO-Rb50 and HXO-RB44
Methods transfection, luciferase reporter assay, Western blot, qRT-PCR, flow cytometry
Expression pattern up-regulated
Functional description MALAT1 might promote retinoblastoma cell autophagy through miR-124-mediated STX17 regulation.
PubMed ID 29073720
Year 2018
Title MALAT1 modulates the autophagy of retinoblastoma cell through miR-124-mediated stx17 regulation.
Drug-related ncRNA NO

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